Nucleoside Analogues with Clinical Potential in Antivirus Chemotherapy: The Effect of Several Thymidine and 2'-Deoxycytidine Analogue 5'-Triphosphates on Purified …
JL Ruth, YC Cheng - Molecular Pharmacology, 1981 - ASPET
… David Derse of this laboratory for providing us with the purified DNA polymerases and much
… Haruhiko Machida, and Jack Fox for providing many of the test compounds as nucleosides. …
… Haruhiko Machida, and Jack Fox for providing many of the test compounds as nucleosides. …
Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs
E De Clercq, RT Walker - Pharmacology & therapeutics, 1984 - Elsevier
… -sensitivity of bacteriophage T3 containing the thymine analogue 5-vinyluracil … of potential
antiviral nucleoside analogs on herpes simplex virus-induced and human cellular thymidine …
antiviral nucleoside analogs on herpes simplex virus-induced and human cellular thymidine …
Inhibition of hepatitis B virus by a novel L-nucleoside, 2'-fluoro-5-methyl-beta-L-arabinofuranosyl uracil
S Balakrishna Pai, SH Liu, YL Zhu… - … and chemotherapy, 1996 - Am Soc Microbiol
… In this report, data for the action of a novel L-nucleoside analog, … L-thymidine analog which
specifically inhibits HBV DNA … HBV DNA synthesis by its action on HBV DNA polymerase. …
specifically inhibits HBV DNA … HBV DNA synthesis by its action on HBV DNA polymerase. …
… -(2-deoxy-2-fluoro-β-d-arabinofuranosyl)adenine on K562 Cellular Metabolism and the Inhibition of Human Ribonucleotide Reductase and DNA Polymerases by Its 5 …
WB Parker, SC Shaddix, CH Chang, EL White… - Cancer research, 1991 - AACR
… of the nucleotide analogues into DNA and the effects of this … effect of several thymidine
and 2'-deoxycytidine analogue 5'-triphosphates on purified human ((.,,() and herpes simplex …
and 2'-deoxycytidine analogue 5'-triphosphates on purified human ((.,,() and herpes simplex …
Human cytomegalovirus-induced DNA polymerase and its interaction with the triphosphates of 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil,-5 …
EC Mar, JF Chiou, YC Cheng, ES Huang - Journal of virology, 1985 - Am Soc Microbiol
… Nucleoside analogues with clinical potential in antivirus chemotherapy: the effect of
several thymidine and 2'-deoxycytidine analogues 5'-triphosphates on purified …
several thymidine and 2'-deoxycytidine analogues 5'-triphosphates on purified …
Inhibitory effect of E-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on herpes simplex virus replication and DNA synthesis
J Descamps, RK Sehgal, E De Clercq… - Journal of …, 1982 - Am Soc Microbiol
… on theactivities of purified viral and cellular DNA polymerases is also … to the concentration
of the nucleoside analog added. The … in human KB cells are similar (0.14 to 0.2 ,uM). The …
of the nucleoside analog added. The … in human KB cells are similar (0.14 to 0.2 ,uM). The …
… and Its Role in the Metabolism of 1-(2′-Deoxy-2′-Fluoro-β-l-Arabinofuranosyl)-5-Methyluracil (Clevudine) and 2′,3′-Didehydro-2′,3′-Dideoxythymidine in …
R Hu, L Li, B Degreve, GE Dutschman… - … and chemotherapy, 2005 - Am Soc Microbiol
… l-nucleoside analogs, the most important intracellular or viral … thymidine analog action
for anti-HBV, anti-Epstein-Barr virus, … TMPK and the partially purified TMPK from CEM cells. …
for anti-HBV, anti-Epstein-Barr virus, … TMPK and the partially purified TMPK from CEM cells. …
Comparison of the phosphorylation of 4′-ethynyl 2′, 3′-dihydro-3′-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs
CH Hsu, R Hu, GE Dutschman, G Yang… - … and chemotherapy, 2007 - Am Soc Microbiol
… against human DNA polymerases, including DNA polymerase γ (34… To exert their anti-HIV
activity, thymidine nucleoside analogs … a partially purified preparation of human liver thymidine …
activity, thymidine nucleoside analogs … a partially purified preparation of human liver thymidine …
Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases
GE Wright, NC Brown - Pharmacology & therapeutics, 1990 - Elsevier
… -Barr virus DNA polymerase and 5′-triphosphates of several antiviral nucleoside analogs
… DNA containing the base analogue 2-aminoadenine: preparation, use as hybridization …
… DNA containing the base analogue 2-aminoadenine: preparation, use as hybridization …
Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human …
JY Liou, P Krishnan, CC Hsieh, GE Dutschman… - Molecular …, 2003 - ASPET
… of thymidine nucleotides. It also may be involved in the … these nucleoside analogs. In this
report, we have described the … of these anti-HIV and -HBV agents on partially purified dCMP …
report, we have described the … of these anti-HIV and -HBV agents on partially purified dCMP …